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What is Jakavi?

The generic name of Jakavi is Ruxolitinib. Jakavi is used to treat adult patients with myelofibrosis. Myelofibrosis is a rare form of blood disorder with a variety of symptoms such as fever, night sweats, bone pain, weight loss. Jakavi is also used to Treat Polycythemia Vera that is intolerant or has not been controlled with other treatment. Polycythemia vera is a rare serious blood disorder with a variety of troublesome symptoms such as itching (pruritus), headache, vision problems, severe burning pain in the hands or feet, and Blood Vessels Clots. An enlarged spleen is one of the characteristics of both myelofibrosis and polycythemia vera. Jakavi is available as tablets (5, 10, 15, and 20 mg). At Cheap Pharmacy Connecticut in South Windham, CT we have genuine healthcare products including Jakavi so that you may get most of its benefits.

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What is Jakavi Used For?

Jakavi is used for:

  • Myelofibrosis in adults who have enlarged spleen or symptoms related to fever, night sweats, bone pain, and weight loss.
  • primary myelofibrosis (also known as chronic idiopathic myelofibrosis)
  • post-polycythemia vera myelofibrosis (linked to an overproduction of red blood cells)
  • post-essential thrombocythaemia myelofibrosis (an overproduction of platelets, components that help the blood to clot)
  • Polycythaemia vera in adults who are resistant or intolerant to treatment with the medicine hydroxyurea.

How To Use Jakavi?

Jakavi is a prescription medicine and should be taken once consulted with a professional and experienced healthcare provider. The patient’s complete blood cell count must be taken before starting Treatment From Jakavi and monitored during treatment. Jakavi treatment is based on your medical condition, laboratory test results, response to treatment, and other medications you may be taking. Do not stop taking Jakavi without consulting your doctor in South Windham, CT. 

Why Jakavi is Prescribed?

Jakavi is used to treat people with an enlarged spleen and other symptoms of myelofibrosis, a rare Type of Blood Cancer. Jakavi is also used to control the number of red blood cells in the blood (hematocrit) for people with the condition polycythemia vera who have not responded to other medications. Jakavi is also used to Treat Graft Versus Host disease in adults and children 12 years of age and older who were treated unsuccessfully with steroid medications by your doctor in South Windham, CT.

What Conditions Does Jakavi Treat?

Jakavi works by blocking a group of enzymes known as Janus kinases (JAKs), which are involved in the production and growth of blood cells. These blood cells migrate to organs including the spleen, causing them to become enlarged. By Blocking Janus Kinases, Jakavi reduces the abnormal production of blood cells, thereby reducing the symptoms of the disease in South Windham, CT. 

Jakavi Dosage

Your Healthcare Professional will determine the appropriate dose of Jakavi for you by taking several factors into account, including:

  • The results of your blood work
  • Certain other medical conditions you may have
  • Other medications you may be taking

Jakavi comes in different dosage strengths 5 mg, 10 mg, 15 mg, 20 mg, and 25 mg. Different people need different doses and dosing may change during treatment. Be sure to take the dose you were prescribed and as often as prescribed. In Myelofibrosis, the recommended starting dose is up to 20 mg twice a day depending on the platelet count. In Polycythaemia Vera, the recommended starting dose by your doctor in South Windham, CT is 10 mg twice a day. If the treatment is not considered effective enough, the dose can be increased by 5 mg up to 25 mg twice a day.

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Side Effects of Jakavi:

Common side effects include but are not limited to:

  • Dizziness.
  • Headache.
  • Tiredness.
  • Weakness.
  • Shortness of breath.
  • Weight gain.
  • Gas.
  • Abdominal pain.
  • Diarrhea.
  • Constipation.
  • Nausea.
  • Itching.
  • Rash.
  • Muscle or joint pain.
  • Swelling of the arms, legs or other parts of the body.
  • Unusual or heavy bleeding or bruising.
  • Fever.
  • Sore throat.
  • Chills.
  • Cough.
  • Chest pain.
  • Night sweats.
  • Urgent urination.
  • Burning, tingling, itching, or skin sensitivity on one side of the body or face with painful rash or blisters.
  • New sores, bumps, discoloration, or other changes to the skin
  • pale skin, tiredness, or shortness of breath.
  • Difficulty moving or keeping your balance.
  • Weakness of the legs or arms that keeps getting worse.
  • Difficulty understanding or speaking.
  • Loss of memory.
  • Vision problems.

Cautions To Take Jakavi:

  • Do not take Jakavi if you have an allergy to it.
  • Do not take Jakavi if you are pregnant.
  • Do not breastfeed if you are taking Jakavi.
  • Do not give Jakavi to a child under the age of 18 years.

Tell your doctor if you have or have had (if appropriate) any of the following medical conditions:
any infection

  • Problems with your kidney.
  • Problems with your liver.
  • Skin cancer.
  • Tuberculosis.
  • Viral hepatitis B.

Do not stop taking Jakavi unless your doctor tells you to.

Frequently Asked Questions

1. How long to take it?

This is a long-term treatment. Your doctor will regularly monitor your condition to make sure that the treatment is having the desired effect. If you interrupt your treatment with Jakavi, your myelofibrosis-related symptoms may come back.

2. Why is Jakavi preferable?

The benefits of taking Jakavi are higher than the risks associated to it. The quality of life of patients treated with Jakavi was improved. Jakavi is of benefit to patients who do not respond or are intolerant to treatment with hydroxyurea, while the safety profile is acceptable.

3. Who should not take Jakavi?

Do not take this medication if you:

  • Are allergic to ruxolitinib or any ingredients of the medication
  • Have a history of an illness called progressive multifocal leukoencephalopathy
4. What should I do in case of an overdose?

In case of overdose, get medical aid immediately. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. Symptoms of overdose may include the following:

  • Unusual bleeding or bruising.
  • Dizziness.
  • Headache.
  • Tiredness.
  • Fever, sore throat, chills, cough, and other signs of infection.

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